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The Kassotis Lab

is open at Wayne State University! We joined the Institute of Environmental Health Sciences (lab home in the Integrative Biosciences Center - IBio), with a co-appointment in the Department of Pharmacology. 

Our lab will be focused on understanding endocrine disrupting chemicals (EDCs) and mixtures, and their potential impacts on human/animal health - with a particular focus on metabolic health (e.g. obesity, etc.). 

My research uses a mixture of cell culture mechanism assays, coupled with zebrafish and mouse models, to characterize molecular mechanisms underpinning potential impacts of EDCs on human and animal health.

Research
Lab News and Updates
May 2022
Latest lab publication is out now in Environmental Health Perspectives!: On the Utility of ToxCast-Based Predictive Models to Evaluate Potential Metabolic Disruption by Environmental Chemicals. 

April 2022
We are recruiting a Research Assistant! Apply here!

Latest set of publications are out now in Biochemical Pharmacology that are authored by several dozen experts in metabolic health, obesity, and chemical obesogens. Articles discuss state of the evidence for molecular mechanisms promoting obesity (I), causal evidence for obesogens (II), and assays available and emerging to measure obesogens (III).

Obesity I: Overview and molecular and biochemical mechanisms.
Obesity II: Establishing causal links between chemical exposures and obesity.
Obesity III: Obesogen assays: Limitations, strengths, and new directions.  

News Coverage: Environmental Health News

March 2022
Kassotis lab attended Society of Toxicology Annual Meeting in San Diego, California, where we shared more on our research into ethoxylated surfactants, unconventional oil and gas chemical mixtures, contraceptives, and liquid crystal monomers!

February 2022
Latest lab publication is out now in Toxics (first direct K99/R00 publication!): Nonylphenol polyethoxylates enhance adipose deposition in developmentally exposed zebrafish. 
Tweets by @cdkassotis

Please feel free to contact me with questions and comments!


Twitter

@cdkassotis

Email

cdkassotis@wayne.edu
“You cannot get through a single day without having an impact on the world around you. What you do makes a difference, and you have to decide what kind of difference you want to make.” — Jane Goodall